ACTIVITY ETHANOL EXTRACT OF MANGGA (Curcuma mangga Val.) FEET UDEM RAT WHITE

The rhizome of mango Curcuma is empirically used as a traditional medicine for the treatment of gastric pain, pain, and inflammation due to hemorrhoids, sore throat, bronchitis, and asthma. The aim of this study was to determine the chemical compound content of secondary metabolites and the activity of the ethanol extract of Temu Mango (Curcuma mangga Val.) on the reduction of carrageenan-induced rat paw edema. The results of a preliminary examination of the chemical content of the rhizome of Intersection mango (Curcuma mango Val.) showed the presence of glycosides, flavonoids, saponins, essential oils, and steroids. In general, the suspension of the ethanol extract of Temu Mango at doses of 50, 100, 200 mg/kg BW gave an anti-inflammatory effect that began to appear in the first half-hour and continued to increase with increasing time. An increase of 2 times the dose of the ethanol extract of Temu Mango showed an anti-inflammatory effect that was not significantly different, but with an increased dose of 4 times, it showed a significant difference. Even the ethanol extract of Intersection mango at a dose of 200 mg/kg BW gave almost the same effect as indomethacin