Frequency resolved cell sizes using optical coherence tomography

Thesis (M.S.)--University of Hawaii at Manoa, 2006.Includes bibliographical references (leaves 50-51).xi, 51 leaves, bound ill. 29 cmHigh resolution Optical Coherence Tomography (OCT) imaging is demonstrated using a superluminescent diode at 1290nm for detecting sizes of tissue cells. This system is fiber-based, built around a Michelson Interferometer. A high speed optical delay line utilizing a resonant scanning mirror at 4kHz in the reference arm allows for fast data acquisition. The choice of a superluminescent diode allows for a cost effective system capable of achieving 16µm axial resolution in air and 12µm axial resolution in tissue with a probing depth of approximately 3mm