Altitude and Endurance Performance in Altitude Natives versus Lowlanders: Insights from Professional Cycling

Introduction: Acute altitude exposure influences exercise performance, although most research, especially regarding altitude natives, comes from laboratory data in non-athletes. Purpose: We analyzed the influence of altitude on real-world cycling performance in top-level professional cyclists attending to whether they were altitude natives or not. Methods: 33 male cyclists (29 ± 5 years) were studied and were classified as lowlanders (N = 19) or altitude natives (N = 14) attending to the altitude of their place of birth (431 ± 380 and 2583 ± 334 meters above sea level (m a.s.l.), respectively). Both groups included top-3 finishers (including winners) in the general classification of Grand Tours and major races. Using data from both training and competitions during years 2013-2020 (8 ± 5 seasons/cyclist), we registered participants' mean maximal power (MMP) for efforts lasting 5 seconds, 30 seconds, 5 minutes and 10 minutes, respectively, at altitudes ranging from 0-500 to >2000 m a.s.l. Results: A significant altitude*MMP interaction effect (two-factor repeated-measures ANOVA) was found in lowlanders (p < 0.001) but not in altitude natives (p = 0.150). In lowlanders, individual performance decreased in a dose-response manner with increasing altitudes compared to sea (or near-sea) level (0-500 m a.s.l.) whereas this trend was much less evident in natives. A significant altitude*MMP*group effect was found (p < 0.001), with non-significant (and overall trivial-to-small differences) between lowlanders and altitude natives for any effort duration at altitudes ≤1500 m a.s.l. but with significant differences at higher altitudes (≥1501 m a.s.l.). Conclusions: Acute altitude exposure influences real-world performance differently in low landers and altitude natives, which might confer a competitive advantage to the latter, particularly in races including efforts at >1500 m a.s.l.Spanish Ministry of Economy and Competitiveness and Fondos Feder (PI18/00139)5.411 JCR (2021) Q1, 8/88 Sport Sciences1.617 SJR (2021) Q1, 12/294 Orthopedics and Sports MedicineNo data IDR 2021UE