Powder processing is plagued by issues of caking and sticking which contribute to the inability to predict the behavior of powders. This leads to unusable products and an increase in unnecessary waste. In this study, new techniques are used and developed to study the effect of capillary condensation under humid conditions using atomic force microscopy (AFM) with &agr;-lactose monohydrate (ALM) as the model powder, one of the most common pharmaceutical excipient in formulation. Phase imaging was used to measure the change in surface moisture on stainless steel and Perpspex® as relative humidity was increased by 10% increments between 15 and 65%. For hydrophilic stainless steel, the low energy (high moisture) regions correlated closely with t...
An atomic force microscope has been used to measure the adhesion between individual silica-glass par...
Atomic force microscopy has been used to study the surface properties of model spray dried powders. ...
Humid environment often creates various problems in fine powder processing and frequently poses a su...
Adhesion between protein and solid surface or between pharmaceutical particle and solid surface is o...
The effect of ambient humidity and adsorbed water can be of critical importance in the processing of...
Moisture induced changes impact the stability of powder systems. Increasing water content influences...
Adhesion of the powders to the punches is a common issue during tableting. This phenomenon is known ...
Due to the strong capillary condensation, the adhesion force between a Si3N4 atomic force microscope...
Forces acting between individual grains in a powder can have a critical and controlling effect on po...
The roughness and softness of interacting surfaces are both important parameters affecting the capil...
A homemade instrument is designed to directly characterize the adhesion between two rigid polymeric ...
The adhesion force between a surface and the tip of an atomic force microscope cantilever has been d...
We have recently shown that atomic force microscopy (AFM) may be an appropriate method for character...
Atomic force microscopy has been used to study the surface properties of model spray dried powders. ...
The primary focus of this dissertation is on characterizing two fundamental forces common to adhesio...
An atomic force microscope has been used to measure the adhesion between individual silica-glass par...
Atomic force microscopy has been used to study the surface properties of model spray dried powders. ...
Humid environment often creates various problems in fine powder processing and frequently poses a su...
Adhesion between protein and solid surface or between pharmaceutical particle and solid surface is o...
The effect of ambient humidity and adsorbed water can be of critical importance in the processing of...
Moisture induced changes impact the stability of powder systems. Increasing water content influences...
Adhesion of the powders to the punches is a common issue during tableting. This phenomenon is known ...
Due to the strong capillary condensation, the adhesion force between a Si3N4 atomic force microscope...
Forces acting between individual grains in a powder can have a critical and controlling effect on po...
The roughness and softness of interacting surfaces are both important parameters affecting the capil...
A homemade instrument is designed to directly characterize the adhesion between two rigid polymeric ...
The adhesion force between a surface and the tip of an atomic force microscope cantilever has been d...
We have recently shown that atomic force microscopy (AFM) may be an appropriate method for character...
Atomic force microscopy has been used to study the surface properties of model spray dried powders. ...
The primary focus of this dissertation is on characterizing two fundamental forces common to adhesio...
An atomic force microscope has been used to measure the adhesion between individual silica-glass par...
Atomic force microscopy has been used to study the surface properties of model spray dried powders. ...
Humid environment often creates various problems in fine powder processing and frequently poses a su...