This study was designed to determine the influence of the following superdisintegrants Ac-Di-Sol, crospovidone and Primojel, in tablets containing a model hydrolyzable drug on the effect of moisture penetration into the tablet cores and the drug stability after aqueous tablet coating. In order to understand the moisture uptake process, the superdisintegrants and tablets made from the superdisintegrants were characterized for their physical properties as well as the coating solutions used. The results of characterization of the superdisintegrants and the tablets showed that the superdisintegrants differ in their mechanisms of action as crospovidone attracted water by the formation of a network of pores, Primojel attracted water by swelling i...
The anionic surfactant sodium dodecylsulfate (SDS) has improved the physical stability of flurbiprof...
Tablets are the most common dosage form in the pharmaceutical industry. Rapid drug release is ensure...
To evaluate the role of polymer-surfactant interactions in drug solubilisation/stabilisation during ...
A physical chemical analysis of the sorption of water molecules by tablets containing cross-linked s...
The purpose of this study was to investigate the efficiency of superdisintegrants in promoting table...
Tablets is the most convenient way to take medication and 70% of the total medicines are dispensed i...
Despite the well-known detrimental effect of moisture on the stability of many pharmaceutical active...
Superdisintegrants are used in some tablet formulations to improve water penetration and disintegrat...
Surface morphology and porosity, moisture sorption, thermal property changes due to water interactio...
The stability of pharmaceutical formulations in non-aqueous media is poorly understood. In order to ...
The poor aqueous solubility of hydrophobic drugs has always been a challenge for formulation scienti...
The aim of this study was to investigate the impact of formulation excipients and solubilizing addit...
<p><b>Objective:</b> To evaluate parameters about wettability, water absorption or swelling of excip...
The objective of this study was to compare the dissolution behavior of tablets prepared from solid d...
We investigated the drug–polymer interactions in nonaqueous and aqueous environments between a poorl...
The anionic surfactant sodium dodecylsulfate (SDS) has improved the physical stability of flurbiprof...
Tablets are the most common dosage form in the pharmaceutical industry. Rapid drug release is ensure...
To evaluate the role of polymer-surfactant interactions in drug solubilisation/stabilisation during ...
A physical chemical analysis of the sorption of water molecules by tablets containing cross-linked s...
The purpose of this study was to investigate the efficiency of superdisintegrants in promoting table...
Tablets is the most convenient way to take medication and 70% of the total medicines are dispensed i...
Despite the well-known detrimental effect of moisture on the stability of many pharmaceutical active...
Superdisintegrants are used in some tablet formulations to improve water penetration and disintegrat...
Surface morphology and porosity, moisture sorption, thermal property changes due to water interactio...
The stability of pharmaceutical formulations in non-aqueous media is poorly understood. In order to ...
The poor aqueous solubility of hydrophobic drugs has always been a challenge for formulation scienti...
The aim of this study was to investigate the impact of formulation excipients and solubilizing addit...
<p><b>Objective:</b> To evaluate parameters about wettability, water absorption or swelling of excip...
The objective of this study was to compare the dissolution behavior of tablets prepared from solid d...
We investigated the drug–polymer interactions in nonaqueous and aqueous environments between a poorl...
The anionic surfactant sodium dodecylsulfate (SDS) has improved the physical stability of flurbiprof...
Tablets are the most common dosage form in the pharmaceutical industry. Rapid drug release is ensure...
To evaluate the role of polymer-surfactant interactions in drug solubilisation/stabilisation during ...