International audienceAccurate segmentation of airways from chest CT scans is crucial for pulmonary disease diagnosis and surgical navigation. However, the intra-class variety of airways and their intrinsic tree-like structure pose challenges to the development of automatic segmentation methods. Previous work that exploits convolutional neural networks (CNNs) does not take context scales into consideration, leading to performance degradation on peripheral bronchiole. We propose the two-step AirwayNet-SE, a Simple-yet-Effective CNNsbased approach to improve airway segmentation. The first step is to adopt connectivity modeling to transform the binary segmentation task into 26-connectivity prediction task, facilitating the model's comprehensio...