A convergent and stereoselective synthesis of 1-oxa-7-azaspiro[5.5]undecane is described. This functional new spiroheterocycle is readily available from acetone ?n?-dimethylhydrazone via a double alkylation and subsequent spiroannulation process
Spiroaminals are an understudied class of heterocycle. Recently, the Barrett group reported a relati...
Quick access to polyfunctional spiroketal (3R)-4-[(2S,6R,8R, 10S)-4,4-bis(ethylthio)-10-hydroxy-8-(2...
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6...
A convergent and stereoselective synthesis of 1-oxa-7-azaspiro[5.5]undecane is described. This funct...
We have developed a short, efficient and enantioselective synthesis of 1,4,7,10-tetraoxa- and 1,7-di...
Many bioactive natural products contain a spiroketal moiety in their complex structure. Recently, si...
MicroreviewInternational audienceThe 1-oxa-7-azaspiro[5.5]undecane, 1-oxa-6-azaspiro[4.5]decane, 1-o...
The spiroketal moiety forms a part of the skeleton of many natural products that present various bio...
International audienceThis work describes a modular efficient route to 10-aza-4-thia-, 10-aza-4-oxa-...
Different chiral spiroketal skeletons are obtained, in a versatile manner, by iterative alkylations ...
(N,N)-spiroaminal is an interesting chemical motif yet it is neglected in synthetic research compar...
AbstractThe nitrogen containing spiro-heterocycle is one of the privileged synthetic motif that cons...
The nitrogen containing spiro-heterocycle is one of the privileged synthetic motif that constitutes ...
Spiroketal pattern appears in the skeleton of many natural products exhibiting various biological ac...
A facile, efficient and unprecedented method for the synthesis of spiro-2H-pyrroles is reported. Whe...
Spiroaminals are an understudied class of heterocycle. Recently, the Barrett group reported a relati...
Quick access to polyfunctional spiroketal (3R)-4-[(2S,6R,8R, 10S)-4,4-bis(ethylthio)-10-hydroxy-8-(2...
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6...
A convergent and stereoselective synthesis of 1-oxa-7-azaspiro[5.5]undecane is described. This funct...
We have developed a short, efficient and enantioselective synthesis of 1,4,7,10-tetraoxa- and 1,7-di...
Many bioactive natural products contain a spiroketal moiety in their complex structure. Recently, si...
MicroreviewInternational audienceThe 1-oxa-7-azaspiro[5.5]undecane, 1-oxa-6-azaspiro[4.5]decane, 1-o...
The spiroketal moiety forms a part of the skeleton of many natural products that present various bio...
International audienceThis work describes a modular efficient route to 10-aza-4-thia-, 10-aza-4-oxa-...
Different chiral spiroketal skeletons are obtained, in a versatile manner, by iterative alkylations ...
(N,N)-spiroaminal is an interesting chemical motif yet it is neglected in synthetic research compar...
AbstractThe nitrogen containing spiro-heterocycle is one of the privileged synthetic motif that cons...
The nitrogen containing spiro-heterocycle is one of the privileged synthetic motif that constitutes ...
Spiroketal pattern appears in the skeleton of many natural products exhibiting various biological ac...
A facile, efficient and unprecedented method for the synthesis of spiro-2H-pyrroles is reported. Whe...
Spiroaminals are an understudied class of heterocycle. Recently, the Barrett group reported a relati...
Quick access to polyfunctional spiroketal (3R)-4-[(2S,6R,8R, 10S)-4,4-bis(ethylthio)-10-hydroxy-8-(2...
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6...