Add to ORKGThe development of protein-based biopharmaceuticals and their introduction on modern medicine brought enormous benefits to the treatment of life-threatening diseases such as cancer, diabetes and neurodegenerative disorders. However, their current high-cost still limits their widespread use. While significant advances at the upstream level have occurred, current purification strategies are unable to cope with high product concentrations resorting to cost-effective approaches. This work entails the development of sustainable downstream processing methodologies for recombinant interferon (IFN) α-2b derived from Escherichia coli using ionic liquids, either by exploring their application as adjuvants in polymer-polymer aqueous two-phase systems ...
The increase of life expectancy has been accompanied by an increment of chronic diseases, with bioph...
Funding: This research was funded by FCT/MCTES (Portugal) through grants SFRH/BD/130965/2017 and COV...
Previous studies have shown that ionic liquids display highly interesting features concerning protei...
Protein biopharmaceuticals, among which interferon alpha-2b (IFNα-2b) that can be used in the treatm...
Improvements on human life expectancy and the lack of effective therapies has led to an increment of...
Biopharmaceuticals are therapeutic drugs produced via biotechnological processes currently applied i...
The development of new drugs has a high impact on the global health, and since the approval of humul...
The increase of life expectancy has been accompanied by an increment of chronic diseases, with bioph...
Over the last decades, society has been facing an increment of chronic diseases due to the higher hu...
Protein biopharmaceuticals, among which interferon alpha-2b (IFNα-2b) that can be used in the treatm...
Remarkable advances in the treatment of chronic diseases have been achieved with biopharmaceutical-b...
Interferon-alpha2b (IFN-α2b) has very high market value since it can be used in treating many diseas...
International audienceMonoclonal antibodies (mAbs) are of crucial interest for therapeutic purposes,...
The advent of biopharmaceuticals in modern medicine brought enormous benefits to diverse human disea...
The purification of intracellular human recombinant interferon-alpha2b (IFN-α2b) from Escherichia co...
The increase of life expectancy has been accompanied by an increment of chronic diseases, with bioph...
Funding: This research was funded by FCT/MCTES (Portugal) through grants SFRH/BD/130965/2017 and COV...
Previous studies have shown that ionic liquids display highly interesting features concerning protei...
Protein biopharmaceuticals, among which interferon alpha-2b (IFNα-2b) that can be used in the treatm...
Improvements on human life expectancy and the lack of effective therapies has led to an increment of...
Biopharmaceuticals are therapeutic drugs produced via biotechnological processes currently applied i...
The development of new drugs has a high impact on the global health, and since the approval of humul...
The increase of life expectancy has been accompanied by an increment of chronic diseases, with bioph...
Over the last decades, society has been facing an increment of chronic diseases due to the higher hu...
Protein biopharmaceuticals, among which interferon alpha-2b (IFNα-2b) that can be used in the treatm...
Remarkable advances in the treatment of chronic diseases have been achieved with biopharmaceutical-b...
Interferon-alpha2b (IFN-α2b) has very high market value since it can be used in treating many diseas...
International audienceMonoclonal antibodies (mAbs) are of crucial interest for therapeutic purposes,...
The advent of biopharmaceuticals in modern medicine brought enormous benefits to diverse human disea...
The purification of intracellular human recombinant interferon-alpha2b (IFN-α2b) from Escherichia co...
The increase of life expectancy has been accompanied by an increment of chronic diseases, with bioph...
Funding: This research was funded by FCT/MCTES (Portugal) through grants SFRH/BD/130965/2017 and COV...
Previous studies have shown that ionic liquids display highly interesting features concerning protei...