Iodine Levels in Pregnant Women with Hyperemesis Gravidarum

OBJECTIVE: Iodine deficiency is a commonly seen problem and associated with pregnancy complications. In this study, we aimed to evaluate urinary iodine status in pregnant women with hyperemesisgravidarumSTUDY DESIGN: A total of 121 women experiencing singleton pregnancies between 6 and 18 weeksof gestation were included in the study. The participants were divided into two groups; group 1 comprised 81 healthy pregnant women, and group 2 comprised 40 pregnant women with HyperemesisGravidarum.RESULTS: Urinary iodine levels were found to be significantly higher in healthy pregnant women thanwomen with Hyperemesis Gravidarum (p=0.008). Urinary iodine was significantly correlated with the urinary ketone (r= -0.252, p=0.005) and FT3 (r= -0.190, p=0.037).CONCLUSION: In pregnant women with hyperemesis gravidarum, oxidative stress was increased, urinary iodine levels were significantly low and negatively correlated with disease severity. Thus, ıodine replacement might be essential to prevent pregnancy complications