The attractiveness of research laboratories in "hard" sciences with actors of contemporary art creation dates back to the 1950s, at the very moment when the figure of the artist-researcher was being forged. Since then, Arts and Science practices, which is work co-produced by an artist and a researcher, have continued to develop, testifying to the growing interest of the art world in questions, methodologies, instruments and images that are elaborated through Sciences. By choosing the Hauts-de-France Region as a field of study and by observing the activities carried out in university laboratories and cultural institutions, this thesis highlights the major role played by actors in higher education and research - art colleges, universities and...