Background: The host response in culture-negative sepsis (CnS) has been marginally explored upon emergency department (ED) admission. It would be of paramount importance to create a clinical prediction rule to support the emergency department physician in identifying septic patients who can be treated with antibiotics immediately without waiting time to draw cultures if they are unlikely to provide useful diagnostic information. Methods: A multivariable logistic regression analysis was applied to identify the independent clinical variables and serum biomarkers of the culture-negative status among 773 undifferentiated septic patients. Those predictors were combined to build a nomogram predictive of CnS. Results: The serum concentrations of s...
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It...
IntroductionMid-regional proadrenomedullin (MR-proADM), a novel biomarker, has recently gained inter...
Introduction: Differentiation between culture-negative bacterial sepsis (BS), culturepositive BS and...
Sepsis and septic shock represent a leading cause of mortality in the Emergency Department (ED) and ...
Background: Sepsis, the life-threatening organ dysfunction due to dysregulated host response to an i...
Background: Biomarkers for early recognition of infection are warranted. The hypothesis of this stud...
Early identification and diagnosis of sepsis and septic shock is vitally important; despite appropri...
INTRODUCTION: Measurement of biomarkers is a potential approach to early assessment and prediction o...
Sepsis is an important healthcare issue worldwide due to the unfavorable clinical outcome and the in...
Biomarkers are widely used to confirm the presence of infection. However, it would be of the greates...
In 2016, an International Consensus has defined sepsis as a “life-threatening organ dysfunction caus...
IF 3.656International audienceBackgroundThe use of novel sepsis biomarkers has increased in recent y...
Abstract: Background: Prediction of the species of pathogen among patients with sepsis within hours ...
Biomarkers are widely used to confirm the presence of infection. However, it would be of the greates...
Copyright © 2015 Silvia Angeletti et al.This is an open access article distributed under the Creativ...
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It...
IntroductionMid-regional proadrenomedullin (MR-proADM), a novel biomarker, has recently gained inter...
Introduction: Differentiation between culture-negative bacterial sepsis (BS), culturepositive BS and...
Sepsis and septic shock represent a leading cause of mortality in the Emergency Department (ED) and ...
Background: Sepsis, the life-threatening organ dysfunction due to dysregulated host response to an i...
Background: Biomarkers for early recognition of infection are warranted. The hypothesis of this stud...
Early identification and diagnosis of sepsis and septic shock is vitally important; despite appropri...
INTRODUCTION: Measurement of biomarkers is a potential approach to early assessment and prediction o...
Sepsis is an important healthcare issue worldwide due to the unfavorable clinical outcome and the in...
Biomarkers are widely used to confirm the presence of infection. However, it would be of the greates...
In 2016, an International Consensus has defined sepsis as a “life-threatening organ dysfunction caus...
IF 3.656International audienceBackgroundThe use of novel sepsis biomarkers has increased in recent y...
Abstract: Background: Prediction of the species of pathogen among patients with sepsis within hours ...
Biomarkers are widely used to confirm the presence of infection. However, it would be of the greates...
Copyright © 2015 Silvia Angeletti et al.This is an open access article distributed under the Creativ...
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It...
IntroductionMid-regional proadrenomedullin (MR-proADM), a novel biomarker, has recently gained inter...
Introduction: Differentiation between culture-negative bacterial sepsis (BS), culturepositive BS and...