Automated Serial Optical Coherence Microscopy toward Statistical 3D Digital Histopathology

we introduce automated serial OCM toward statistical 3D digital histopathology. Our research is the extension of previous work in order to enhance the process of imaging acquisition. Our approach has three unique features, (1) surface tracking, (2) single body and automated system combined vibratome and microscopic imaging head, and (3) selection of magnification. In validation test, various mouse organs were imaged and quantified at the region of interest which presented less labor and shorten image acquisition time compared to previous works