Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection.
- Dhillon, Permesh Singh
- Butt, Waleed
- Podlasek, Anna
- McConachie, Norman
- Lenthall, Robert
- Nair, Sujit
- Malik, Luqman
- Bhogal, Pervinder
- Makalanda, Hegoda Levansri Dilrukshan
- Spooner, Oliver
- Krishnan, Kailash
- Sprigg, Nikola
- Mortimer, Alex
- Booth, Thomas Calvert
- Lobotesis, Kyriakos
- White, Philip
- James, Martin A
- Bath, Philip
- Dineen, Robert A
- England, Timothy J
DOIAbstract
BACKGROUND The effectiveness and safety of endovascular thrombectomy (EVT) in the late window (6-24 hours) for acute ischemic stroke (AIS) patients selected without advanced imaging is undetermined. We aimed to assess clinical outcomes and the relationship with time-to-EVT treatment beyond 6 hours of stroke onset without advanced neuroimaging. METHODS Patients who underwent EVT selected with non-contrast CT/CT angiography (without CT perfusion or MR imaging), between October 2015 and March 2020, were included from a national stroke registry. Functional and safety outcomes were assessed in both early (<6 hours) and late windows with time analyzed as a continuous variable. RESULTS Among 3278 patients, 2610 (79.6%) and 668 (20.4...
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