Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection
- Dhillon, P. S.
- Butt, W.
- Podlasek, A.
- McConachie, N.
- Lenthall, R.
- Nair, S.
- Malik, L.
- Bhogal, P.
- Makalanda, H. L. D.
- Spooner, O.
- Krishnan, K.
- Sprigg, N.
- Mortimer, A.
- Booth, T. C.
- Lobotesis, K.
- White, P.
- James, M. A.
- Bath, P.
- Dineen, R. A.
- England, T. J.
DOIAbstract
BACKGROUND: The effectiveness and safety of endovascular thrombectomy (EVT) in the late window (6-24 hours) for acute ischemic stroke (AIS) patients selected without advanced imaging is undetermined. We aimed to assess clinical outcomes and the relationship with time-to-EVT treatment beyond 6 hours of stroke onset without advanced neuroimaging. METHODS: Patients who underwent EVT selected with non-contrast CT/CT angiography (without CT perfusion or MR imaging), between October 2015 and March 2020, were included from a national stroke registry. Functional and safety outcomes were assessed in both early (<6 hours) and late windows with time analyzed as a continuous variable. RESULTS: Among 3278 patients, 2610 (79.6%) and 668 (20.4%) patients ...
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