Objectives To investigate if maturity status was associated with injury risk in male academy soccer players. Design Prospective cohort surveillance study. Setting Professional soccer academies. Participants 501 players (aged 9–23 years) from eight academies in England, Spain, Uruguay and Brazil. Main outcome measures Players were grouped by maturity offset as pre-peak height velocity (PHV), circa-PHV, post-PHV or adult. Injury prevalence proportion (IPP) and days missed were recorded for one season per player, with training/match exposure recorded in a sub-sample (n = 166). Results IPP for all injuries combined increased with advancing maturity, with circa-PHV (p = 0.032), post-PHV (p < 0.001) and adult (p < 0.001) higher than pre-PHV. IPP ...