Acceptability of a novel levofloxacin dispersible tablet formulation in young children exposed to multidrug-resistant tuberculosis
- Purchase, Susan E.
- Garcia-Prats, Anthony J.
- De Koker, Petra
- Draper, Heather R.
- Osman, Muhammad
- Seddon, James A.
- Schaaf, H. Simon
- Hesseling, Anneke C.
Publication date
June 2019
DOI Publisher
Ovid Technologies (Wolters Kluwer Health)Abstract
Levofloxacin is used for the treatment and prevention of multidrug-resistant tuberculosis in children, but current adult formulations are poorly palatable. A questionnaire administered to caregivers of 27 children taking a novel 100 mg dispersible taste-masked levofloxacin tablet found the new formulation to be more palatable (69%) and easier to prepare (81%) than the adult formulation. This formulation may assist children to better adhere to anti-tuberculous therapy
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