A Method to Generate Experimental Aerosol with Similar Particle Size Distribution to Atmospheric Aerosol

The SARS-CoV virus spreads in the atmosphere mainly in the form of aerosols. Particle air filters are widely used in indoor heating, ventilation, and air-conditioning (HVAC) systems and filtration equipment to reduce aerosol concentration and improve indoor air quality. Requirements arise to rate filters according to their mass-based filtration efficiency. The size distribution of test aerosol greatly affects the measurement results of mass-based filtration efficiency and dust loading of filters, as well as the calibration of optical instruments for fine-particle (PM2.5) mass concentration measurement. The main objective of this study was to find a new method to generate a chemically nontoxic aerosol with a similar particle size distribution to atmospheric aerosol. We measured the size distribution of aerosols generated by DEHS (di-ethyl-hexyl-sebacate), PSL (poly-styrene latex), olive oil, and 20% sucrose solution with a collision nebulizer in a wide range of 15 nm–20 μm. Individually, none of the solutions generated particles that share a similar size distribution to atmospheric aerosol. We found that the 20% sucrose solution + olive oil mixture solution (Vss:Voo = 1:2) could be used to generate a chemically nontoxic aerosol with similar particle number/volume size distribution to the atmospheric aerosol (t-test, p 2.5 concentration measurement instruments. The average relative difference measured by a tapered element oscillating microbalance (TEOM) and a Dusttrak Model 8530 (calibrated by aerosol generated by the new method) was smaller than 5.8% in the real-situation measurement