Vaccine effectiveness against infection and onwards transmission of COVID-19 : analysis of Belgian contact tracing data, January-June 2021
- Braeye, Toon
- Cornelissen, Laura
- Catteau, Lucy
- Haarhuis, Freek
- Proesmans, Kristiaan
- De Ridder, Karin
- Djiena, Achille
- Mahieu, Romain
- De Leeuw, Frances
- Dreuw, Alex
- Hammami, Naima
- Quoilin, Sophie
- Van Oyen, Herman
- Wyndham-Thomas, Chloé
- Van Cauteren, Dieter
DOIAbstract
In Belgium, high-risk contacts of an infected person were offered PCR-testing irrespective of their vacci-nation status. We estimated vaccine effectiveness (VE) against infection and onwards transmission, con-trolling for previous infections, household-exposure and temporal trends. We included 301,741 tests from 25 January to 24 June 2021. Full-schedule vaccination was associated with significant protection against infection. In addition, mRNA-vaccines reduced onward transmission: VE-estimates increased to >90% when index and contact were fully vaccinated. The small number of viral-vector vaccines included limited interpretability. (C) 2021 The Author(s). Published by Elsevier Ltd
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