Background SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes over the course of the pandemic. The severity of a SARS-CoV-2 infection could partly depend on these viral genetic characteristics. Here, we present a general conceptual framework that allows to study the effect of SARS-CoV-2 variants on COVID-19 disease severity among hospitalized patients. Methods A causal model is defined and visualized using a Directed Acyclic Graph (DAG), in which assumptions on the relationship between (confounding) variables are made explicit. Various DAGs are presented to explore specific study design options and the risk for selection bias. Next, the data infrastructure specific to the COVID-19 surveillance in Belgium is des...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
Background: The COVID-19 pandemic has had an immeasurable impact, affecting healthcare systems, the ...
Abstract Background SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes...
BACKGROUND: SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes over th...
BACKGROUND: Differences in the genetic material of severe acute respiratory syndrome coronavirus 2 (...
INTRODUCTION: The pathogenesis of COVID-19 depends on the interplay between host characteristics, vi...
Throughout the COVID-19 pandemic, valuable datasets have been collected on the effects of the virus ...
International audienceBackground: We conducted this review to summarize the relation between viral m...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
Background: The COVID-19 pandemic has had an immeasurable impact, affecting healthcare systems, the ...
Abstract Background SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes...
BACKGROUND: SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes over th...
BACKGROUND: Differences in the genetic material of severe acute respiratory syndrome coronavirus 2 (...
INTRODUCTION: The pathogenesis of COVID-19 depends on the interplay between host characteristics, vi...
Throughout the COVID-19 pandemic, valuable datasets have been collected on the effects of the virus ...
International audienceBackground: We conducted this review to summarize the relation between viral m...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
This retrospective multi-center matched cohort study assessed the risk for severe COVID-19 (combinat...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
The genetic make-up of an individual contributes to the susceptibility and response to viral infecti...
Background: The COVID-19 pandemic has had an immeasurable impact, affecting healthcare systems, the ...