A broad survey to determine paediatric clinical trial requirements within Belgium

Update on the progression of clinical trials within BPCRN/c4c. Patient Engagement activities were illustrated. Results of a questionnaire, conducted in 2021, portrayed which involving the majority of sites connected within BPCRN. Within the Belgian network, around 4 (30%) of sites do not have a paediatric clinical trial unit to support the trial. All sites agreed or strongly agreed that a national hub is useful for the site to conduct clinical trials. The majority namely 11 (84%) of sites identified human resources as a core improvement need for sites, specifically finding dedicated clinical research nurses and finding time for principal investigators (PI) to perform study tasks aside from clinical work. A strong need for financing of infrastructure from 10 (76%) of sites is acknowledged for consultation areas, imaging, and a biobank structure. On the contrary, 12 (92%) of sites did not regard study-specific courses as a priority. In order to foster sustainable development of new medicines in paediatric diseases, site need’s must to be taken into account and prioritized. The primary need is in human resources and financing of infrastructure. Further investigation into how a centralized organization can support is needed