From a survey of the recent literature on chronic intraspinal morphine administration for cancer pain concerning 412 cases, the present authors observe that: 1. data regarding follow-up on pain relief and complications are lacking; 2. continuous administration by closed systems shows more efficacy in long-term pain relief; 3. tolerance, although not reported by all authors, is present and becomes remarkable in prolonged administration; 4. serious side-effects are less frequent with the epidural administration technique. These data are confirmed by the present authors' clinical experience of 22 patients treated with epidural morphine administration and 53 patients treated with intrathecal morphine. The widespread use of these methods is limi...
The efficacy of spinal opioids is well known, the analgesia is potent and long lasting, due to the c...
Background. Sufficient analgesia for cancer pain is sometimes difficult to achieve with conven-tiona...
The World Health Organization guidelines for cancer pain relief have been proven efficacious in 90% ...
Long-term analgesia with epidural morphine (EM) is a new tool in the management of intractable cance...
Between 10% and 20% of cancer pain patients fail to obtain adequate pain relief despite comprehensiv...
Abstract Patients who have refractory cancer pain suffer both physically and psychologically. Cancer...
In pre-terminal and terminal gynaecological patients with persistent cancer pain, now it is possible...
Pain is prevalent in advanced malignancies; however, some patients cannot get adequate pain relief b...
Item does not contain fulltextPain in patients with cancer can be refractory to pharmacological trea...
Copyright © 2015 Ying Huang et al. This is an open access article distributed under the Creative Com...
Introduction: A substantial number of patients with cancer suffer considerable pain at some point du...
Spinal administration of morphine and other opiates has been used in clinical practice since many ye...
Intrathecal drug delivery appeared in the early eighties and allows to administer high concentrate a...
Morphine sulphate 3 or 4 mg was administered to the extradural space in five volunteers. Morphine 10...
The use of morphine in the treatment of cancer pain is widely accepted among people taking care of c...
The efficacy of spinal opioids is well known, the analgesia is potent and long lasting, due to the c...
Background. Sufficient analgesia for cancer pain is sometimes difficult to achieve with conven-tiona...
The World Health Organization guidelines for cancer pain relief have been proven efficacious in 90% ...
Long-term analgesia with epidural morphine (EM) is a new tool in the management of intractable cance...
Between 10% and 20% of cancer pain patients fail to obtain adequate pain relief despite comprehensiv...
Abstract Patients who have refractory cancer pain suffer both physically and psychologically. Cancer...
In pre-terminal and terminal gynaecological patients with persistent cancer pain, now it is possible...
Pain is prevalent in advanced malignancies; however, some patients cannot get adequate pain relief b...
Item does not contain fulltextPain in patients with cancer can be refractory to pharmacological trea...
Copyright © 2015 Ying Huang et al. This is an open access article distributed under the Creative Com...
Introduction: A substantial number of patients with cancer suffer considerable pain at some point du...
Spinal administration of morphine and other opiates has been used in clinical practice since many ye...
Intrathecal drug delivery appeared in the early eighties and allows to administer high concentrate a...
Morphine sulphate 3 or 4 mg was administered to the extradural space in five volunteers. Morphine 10...
The use of morphine in the treatment of cancer pain is widely accepted among people taking care of c...
The efficacy of spinal opioids is well known, the analgesia is potent and long lasting, due to the c...
Background. Sufficient analgesia for cancer pain is sometimes difficult to achieve with conven-tiona...
The World Health Organization guidelines for cancer pain relief have been proven efficacious in 90% ...