Background & Aims: Fatty liver disease (FLD) is a growing epidemic that is expected to be the leading cause of end-stage liver disease within the next decade. Both environmental and genetic factors contribute to the susceptibility of FLD. Several genetic variants contributing to FLD have been identified in exome-wide association studies. However, there is still a missing hereditability indicating that other genetic variants are yet to be discovered. Methods: To find genes involved in FLD, we first examined the association of missense and nonsense variants with alanine aminotransferase at an exome-wide level in 425,671 participants from the UK Biobank. We then validated genetic variants with liver fat content in 8930 participants in whom...
Nonalcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease. Using a proxy ...
Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cir...
BACKGROUND Exome sequencing in hundreds of thousands of persons may enable the identification of rar...
Background & Aims: Fatty liver disease (FLD) is a growing epidemic that is expected to be the le...
BACKGROUND: Understanding the genetics of liver disease has the potential to facilitate clinical ris...
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic var...
Contains fulltext : 95930.pdf (postprint version ) (Open Access)Nonalcoholic fatty...
Summary: Non-alcoholic fatty liver disease (NAFLD) is a complex disease linked to several chronic di...
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver disorders and has a strong h...
Background & Aims: Genetic factors associated with nonalcoholic fatty liver disease (NAFLD) rema...
Background & Aims: Genetic factors associated with non-alcoholic fatty liver disease (NAFLD) rem...
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic var...
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular...
Nonalcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease. Using a proxy ...
Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cir...
BACKGROUND Exome sequencing in hundreds of thousands of persons may enable the identification of rar...
Background & Aims: Fatty liver disease (FLD) is a growing epidemic that is expected to be the le...
BACKGROUND: Understanding the genetics of liver disease has the potential to facilitate clinical ris...
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic var...
Contains fulltext : 95930.pdf (postprint version ) (Open Access)Nonalcoholic fatty...
Summary: Non-alcoholic fatty liver disease (NAFLD) is a complex disease linked to several chronic di...
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver disorders and has a strong h...
Background & Aims: Genetic factors associated with nonalcoholic fatty liver disease (NAFLD) rema...
Background & Aims: Genetic factors associated with non-alcoholic fatty liver disease (NAFLD) rem...
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic var...
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular...
Nonalcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease. Using a proxy ...
Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cir...
BACKGROUND Exome sequencing in hundreds of thousands of persons may enable the identification of rar...