Sequential enhancer state remodelling defines human gremlin competence and specification

Tang, WC
Castillo-Venzor, A
Gruhn, WH
Kobayashi, T
Penfold, CA
Morgan, MD
Sun, D
Irie, N
Surani, A

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Publication date

March 2022

DOI

10.17863/CAM.82108

Publisher

Nature Cell Biology

Abstract

Germline-soma segregation is a fundamental event during mammalian embryonic development. Here we establish the epigenetic principles of human primordial germ cell (hPGC) development using in vivo hPGCs and stem cell models recapitulating gastrulation.Wellcome Trust PhD studentship RG86341/PRZI/045 Aracely Castillo-Venzor Wellcome Trust PhD studentship (109146/Z/15/Z) Dawei Su

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Sequential enhancer state remodelling defines human gremlin competence and specification

Abstract

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Sequential enhancer state remodelling defines human gremlin competence and specification

Abstract

Extracted data

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