Neuropathic pain arises from damage or dysfunction of the peripheral or central nervous system and manifests itself in a wide variety of sensory symptoms and cognitive disorders. Many studies demonstrate the role of neuropathic pain-induced neuroinflammation in behavioral disorders. For effective neuropathic pain treatment, an integrative approach is required, which simultaneously affects several links of pathogenesis. One promising candidate for this role is synaptamide (N-docosahexaenoylethanolamine), which is an endogenous metabolite of docosahexaenoic acid. In this study, we investigated the activity of synaptamide on mice behavior and hippocampal plasticity in neuropathic pain induced by spared nerve injury (SNI). We found a beneficial...
Summary: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral or ...
SummaryNeuropathic pain is caused by long-term modifications of neuronal function in the peripheral ...
Spinal cord injury (SCI) impairs mobility and often results in complications like intractable neurop...
Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to am...
Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to am...
Background: Enhanced supraspinal glutamate levels following nerve injury are associated with pathoph...
This study investigated whether metabotropic glutamate receptor (mGluR) 5 and 8 are involved in the ...
At present, the study of the neurotropic activity of polyunsaturated fatty acid ethanolamides (N-acy...
Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology that involve...
Background and aims: Although neuropathic pain is known to negatively affect cognition, the neural m...
D-Aspartate (D-Asp) is a free D-amino acid detected in multiple brain regions and putative precursor...
D-Aspartate (D-Asp) is a free D-amino acid detected in multiple brain regions and putative precursor...
Patients with chronic pain usually suffer from working memory deficits, which may decrease their int...
Abstract Neuropathic pain is generally defined as a chronic pain state resulting from ...
Summary: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral or ...
SummaryNeuropathic pain is caused by long-term modifications of neuronal function in the peripheral ...
Spinal cord injury (SCI) impairs mobility and often results in complications like intractable neurop...
Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to am...
Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to am...
Background: Enhanced supraspinal glutamate levels following nerve injury are associated with pathoph...
This study investigated whether metabotropic glutamate receptor (mGluR) 5 and 8 are involved in the ...
At present, the study of the neurotropic activity of polyunsaturated fatty acid ethanolamides (N-acy...
Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology that involve...
Background and aims: Although neuropathic pain is known to negatively affect cognition, the neural m...
D-Aspartate (D-Asp) is a free D-amino acid detected in multiple brain regions and putative precursor...
D-Aspartate (D-Asp) is a free D-amino acid detected in multiple brain regions and putative precursor...
Patients with chronic pain usually suffer from working memory deficits, which may decrease their int...
Abstract Neuropathic pain is generally defined as a chronic pain state resulting from ...
Summary: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral or ...
SummaryNeuropathic pain is caused by long-term modifications of neuronal function in the peripheral ...
Spinal cord injury (SCI) impairs mobility and often results in complications like intractable neurop...