Iron is an essential element for virtually all living things. Body iron levels are tightly controlled as both increased iron levels and iron deficiency are associated with many clinical conditions. Increased iron levels are associated with a worse prognosis in some cancers, so understanding the role of iron in cancer development has thus been an active area of research. Regulated forms of cell death are important in development and disease pathogenesis. In this Medicine in Focus review article, we discuss the role of iron in cancer, and ferroptosis, a new form of iron-regulated cell death triggered by increased iron and peroxidation of lipids. We also review the pathogenesis of cancer, potential therapeutics for targeting the increased requ...
One of the key challenges in cancer research how to effectively kill cancer cells while leaving the ...
Iron is essential for the growth and proliferation of cells, as well as for many biological processe...
Iron (Fe) is the fourth most common element in the earth's crust, and plays a significant role in th...
Iron is an essential element for virtually all living things. Body iron levels are tightly controlle...
A non-apoptotic iron-dependent form of Regulated Cell Death (RCD) known as ferroptosis is brought on...
Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, wh...
Despite significant developments and persistent efforts by scientists, cancer is one of the primary ...
Iron is an essential trace element for the human body, and its deficiency or excess can induce a var...
Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained occurrence ...
Breast cancer (BC) is the most common malignancy among women worldwide. The discovery of regulated c...
Significance:- In this review, the dual nature of both iron and reactive oxygen species (ROS) will...
Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron metabolis...
Demanded as an essential trace element that supports cell growth and basic functions, iron can be ha...
Cell death is essential for the normal metabolism of human organisms. Ferroptosis is a unique regula...
[[abstract]]Breast cancer (BC) is the most common malignancy among women worldwide. The dis-covery o...
One of the key challenges in cancer research how to effectively kill cancer cells while leaving the ...
Iron is essential for the growth and proliferation of cells, as well as for many biological processe...
Iron (Fe) is the fourth most common element in the earth's crust, and plays a significant role in th...
Iron is an essential element for virtually all living things. Body iron levels are tightly controlle...
A non-apoptotic iron-dependent form of Regulated Cell Death (RCD) known as ferroptosis is brought on...
Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, wh...
Despite significant developments and persistent efforts by scientists, cancer is one of the primary ...
Iron is an essential trace element for the human body, and its deficiency or excess can induce a var...
Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained occurrence ...
Breast cancer (BC) is the most common malignancy among women worldwide. The discovery of regulated c...
Significance:- In this review, the dual nature of both iron and reactive oxygen species (ROS) will...
Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron metabolis...
Demanded as an essential trace element that supports cell growth and basic functions, iron can be ha...
Cell death is essential for the normal metabolism of human organisms. Ferroptosis is a unique regula...
[[abstract]]Breast cancer (BC) is the most common malignancy among women worldwide. The dis-covery o...
One of the key challenges in cancer research how to effectively kill cancer cells while leaving the ...
Iron is essential for the growth and proliferation of cells, as well as for many biological processe...
Iron (Fe) is the fourth most common element in the earth's crust, and plays a significant role in th...