After sequential cycles of urbanization and suburbanization, European cities underwent a (more or less intense) re-urbanization wave. The present study analyzes short-term population dynamics in the core of a large metropolitan region (Milan, northern Italy), providing evidence of spatially-heterogeneous re-urbanization characterized by spatially-complex population growth (or shrinkage) at a local scale. Population dynamics over 1999–2017 were assessed in 88 urban districts partitioning Milan′s municipal area and projected up to 2036 for the same spatial units. Empirical results identify spatially-complex and temporally non-linear dynamics with expanding or declining districts distributed heterogeneously across the study area. Multivariate ...