Nano-fibers as a modern extraction sorbents for extraction of samples in chromatographic analysis

Charles University, Faculty of Pharmacy in Hradec Králové Training workplace Department of Analytical Chemistry Doctoral degree program Pharmaceutical Analysis Candidate Mgr. Hedvika Raabová Supervisor prof. RNDr. Dalibor Šatínský, Ph.D. Advisor assoc. prof. PharmDr. Lucie Chocholoušová Havlíková, Ph. D. Title of Doctoral Thesis Nanofibers as modern extraction sorbents for sample extraction in chromatographic analysis Extraction techniques represent one of the most common approaches to sample handling. The analytes of interest can be isolated easily even from complex matrices, especially by solid-phase extraction (SPE). Therefore, this technique became very popular and routinely used in laboratories. The variety of commercially available sorbents has made this method even more attractive. Nevertheless, the new sorbent materials are still looked for because of the broadening spectrum of analyzed substances and the increasing demands on selectivity and extraction efficiency. Nanomaterials have been increasingly associated with these properties over the last ten years. Therefore, they are receiving more and more attention related to extraction procedures. The dissertation thesis is focused on the application of nanofibrous polymers as innovative sorbents for solid-phase extraction. First, the..