The discovery of antibiotics more than 80 years ago has led to considerable improvements in human and animal health. Although antibiotic resistance in environmental bacteria is ancient, resistance in human pathogens is thought to be a modern phenomenon that is driven by the clinical use of antibiotics1. Here we show that particular lineages of methicillin-resistant Staphylococcus aureus—a notorious human pathogen—appeared in European hedgehogs in the pre-antibiotic era. Subsequently, these lineages spread within the local hedgehog populations and between hedgehogs and secondary hosts, including livestock and humans. We also demonstrate that the hedgehog dermatophyte Trichophyton erinacei produces two β-lactam antibiotics that provide a natu...
Recently, a novel mec gene conferring beta-lactam resistance in Staphylococcus aureus has been disco...
Staphylococcus aureus is a human pathobiont (i.e., a commensal microorganism that is potentially pat...
Antibiotic resistance is a serious problem in human and animal infections. Heavy use of antibiotics...
The discovery of antibiotics more than 80 years ago has led to considerable improvements in human an...
The discovery of antibiotics more than 80 years ago has led to considerable improvements in human an...
Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mecC gene (m...
Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mecC gene (m...
Abstract Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mec...
OBJECTIVES:A recent study from Sweden showed that European hedgehogs may constitute a reservoir for ...
<div><p>Recently, a novel <i>mec</i> gene conferring beta-lactam resistance in <i>Staphylococcus aur...
In 2011 mecC, a new mecA gene homologue, was described in a bovine isolate in the UK. Since then, me...
Recently, a novel mec gene conferring beta-lactam resistance in Staphylococcus aureus has been disco...
Staphylococcus aureus is a human pathobiont (i.e., a commensal microorganism that is potentially pat...
Antibiotic resistance is a serious problem in human and animal infections. Heavy use of antibiotics...
The discovery of antibiotics more than 80 years ago has led to considerable improvements in human an...
The discovery of antibiotics more than 80 years ago has led to considerable improvements in human an...
Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mecC gene (m...
Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mecC gene (m...
Abstract Background A high carriage rate of methicillin-resistant Staphylococcus aureus with the mec...
OBJECTIVES:A recent study from Sweden showed that European hedgehogs may constitute a reservoir for ...
<div><p>Recently, a novel <i>mec</i> gene conferring beta-lactam resistance in <i>Staphylococcus aur...
In 2011 mecC, a new mecA gene homologue, was described in a bovine isolate in the UK. Since then, me...
Recently, a novel mec gene conferring beta-lactam resistance in Staphylococcus aureus has been disco...
Staphylococcus aureus is a human pathobiont (i.e., a commensal microorganism that is potentially pat...
Antibiotic resistance is a serious problem in human and animal infections. Heavy use of antibiotics...