Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues investigating the associations between genetically-proxied inhibition of antihypertensive drug targets and risk of common cancer subtypes using Mendelian randomization
Mendelian randomization is an epidemiological technique that compares disease risk in groups of indi...
Phenotypic heterogeneity at genomic loci encoding drug targets can be exploited by multivariable Men...
Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the...
Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Evidence on the validity of drug targets from randomized trials is reliable but typically expensive ...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effect...
Different statistical approaches have been implemented to overcome the limitations that typically an...
Understanding the causal role of biomarkers in cardiovascular and other diseases is crucial in order...
Large-scale genome-wide association studies conducted over the last decade have uncovered numerous g...
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effect...
Mendelian randomization (MR) is an approach that uses genetic variants associated with a modifiable ...
Mendelian randomization is an epidemiological technique that compares disease risk in groups of indi...
Phenotypic heterogeneity at genomic loci encoding drug targets can be exploited by multivariable Men...
Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the...
Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Evidence on the validity of drug targets from randomized trials is reliable but typically expensive ...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be appro...
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effect...
Different statistical approaches have been implemented to overcome the limitations that typically an...
Understanding the causal role of biomarkers in cardiovascular and other diseases is crucial in order...
Large-scale genome-wide association studies conducted over the last decade have uncovered numerous g...
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effect...
Mendelian randomization (MR) is an approach that uses genetic variants associated with a modifiable ...
Mendelian randomization is an epidemiological technique that compares disease risk in groups of indi...
Phenotypic heterogeneity at genomic loci encoding drug targets can be exploited by multivariable Men...
Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the...