Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water
- Danhua Dai
- Xianwei Wang
- Yiwei Liu
- Xiao-Liang Yang
- Clemens Glaubitz
- Vasyl Denysenkov
- Xiao He
- Thomas Prisner
- Jiafei Mao
Publication date
November 2021
DOI Publisher
Springer Science and Business Media LLC Journal
Nature CommunicationsAbstract
Dynamic nuclear polarization (DNP) greatly improves the NMR sensitivity, but its implementation in aqueous solutions is challenging. Here the authors demonstrate carbon polarization enhancement via in situ Overhauser DNP in small biomolecules in water at room temperature and high magnetic field
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