Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study : a prospective, multicentre cohort study
- Sullivan, MK
- Lees, JS
- Drake, TM
- Docherty, AB
- Oates, G
- Hardwick, HE
- Russell, CD
- Merson, L
- Dunning, J
- Nguyen-Van-Tam, JS
- Openshaw, P
- Harrison, EM
- Baillie, JK
- Baillie, JK
- Semple, MG
- Openshaw, PJM
- Carson, G
- Alex, B
- Bach, B
- Barclay, WS
- Bogaert, D
- Chand, M
- Cooke, GS
- Docherty, AB
- Dunning, J
- da Silva Filipe, A
- Fletcher, T
- Green, CA
- Harrison, EM
- Hiscox, JA
- Ho, AYW
- Horby, PW
- Ijaz, S
- Khoo, S
- Klenerman, P
- Law, A
- Lim, WS
- Mentzer, AJ
- Merson, L
- Meynert, AM
- Noursadeghi, M
- Moore, SC
- Palmarini, M
- Paxton, WA
- Pollakis, G
- Price, N
- Rambaut, A
- Robertson, DL
- Russell, CD
- Sancho-Shimizu, V
- Scott, JT
- de Silva, T
- Sigfrid, L
- Solomon, T
- Sriskandan, S
- Stuart, D
- Summers, C
- Tedder, RS
- Thomson, EC
- Thompson, AAR
- Thwaites, RS
- Turtle, LCW
- Zambon, M
- Hardwick, H
- Donohue, C
- Lyons, R
- Griffiths, F
- Oosthuyzen, W
- Norman, L
- Pius, R
- Drake, TM
- Fairfield, CJ
- Knight, SR
- Mclean, KA
- Murphy, D
- Shaw, CA
- Dalton, J
- Girvan, M
- Saviciute, E
- Roberts, S
- Harrison, J
- Marsh, L
- Connor, M
- Halpin, S
- Jackson, C
- Gamble, C
- Leeming, G
- Law, A
- Wham, M
- Clohisey, S
- Hendry, R
- Scott-Brown, J
- Greenhalf, W
- Shaw, V
- McDonald, S
- Keating, S
- Ahmed, KA
- Armstrong, JA
- Ashworth, M
- Asiimwe, IG
- Bakshi, S
- Barlow, SL
- Booth, L
- Brennan, B
- Bullock, K
- Catterall, BWA
- Clark, JJ
- Clarke, EA
- Cole, S
- Cooper, L
- Cox, H
- Davis, C
- Dincarslan, O
- Dunn, C
- Dyer, P
- Elliott, A
- Evans, A
- Finch, L
- Fisher, LWS
- Foster, T
- Garcia-Dorival, I
- Greenhalf, W
- Gunning, P
- Hartley, C
- Jensen, RL
- Jones, CB
- Jones, TR
- Khandaker, S
- King, K
- Kiy, RT
- Koukorava, C
- Lake, A
- Lant, S
- Latawiec, D
- Lavelle-Langham, L
- Lefteri, D
- Lett, L
- Livoti, LA
- Mancini, M
- McDonald, S
- McEvoy, L
- McLauchlan, J
- Metelmann, S
- Miah, NS
- Middleton, J
- Mitchell, J
- Moore, SC
- Murphy, EG
- Penrice-Randal, R
- Pilgrim, J
- Prince, T
- Reynolds, W
- Ridley, PM
- Sales, D
- Shaw, VE
- Shears, RK
- Small, B
- Subramaniam, KS
- Szemiel, A
- Taggart, A
- Tanianis-Hughes, J
- Thomas, J
- Trochu, E
- van Tonder, L
- Wilcock, E
- Zhang, JE
- Flaherty, L
- Maziere, N
- Cass, E
- Carracedo, AD
- Carlucci, N
- Holmes, A
- Massey, H
- Murphy, L
- Wrobel, N
- McCafferty, S
- Morrice, K
- MacLean, A
- Adeniji, K
- Agranoff, D
- Agwuh, K
- Ail, D
- Aldera, EL
- Alegria, A
- Angus, B
- Ashish, A
- Atkinson, D
- Bari, S
- Barlow, G
- Barnass, S
- Barrett, N
- Bassford, C
- Basude, S
- Baxter, D
- Beadsworth, M
- Bernatoniene, J
- Berridge, J
- Best, N
- Bothma, P
- Chadwick, D
- Brittain-Long, R
- Bulteel, N
- Burden, T
- Burtenshaw, A
- Caruth, V
- Chadwick, D
- Chambler, D
- Chee, N
- Child, J
- Chukkambotla, S
- Clark, T
- Collini, P
- Cosgrove, C
- Cupitt, J
- Cutino-Moguel, M-T
- Dark, P
- Dawson, C
- Dervisevic, S
- Donnison, P
- Douthwaite, S
- DuRand, I
- Dushianthan, A
- Dyer, T
- Evans, C
- Eziefula, C
- Fegan, C
- Finn, A
- Fullerton, D
- Garg, S
- Garg, S
- Garg, A
- Gkrania-Klotsas, E
- Godden, J
- Goldsmith, A
- Graham, C
- Hardy, E
- Hartshorn, S
- Harvey, D
- Havalda, P
- Hawcutt, DB
- Hobrok, M
- Hodgson, L
- Hormis, A
- Jacobs, M
- Jain, S
- Jennings, P
- Kaliappan, A
- Kasipandian, V
- Kegg, S
- Kelsey, M
- Kendall, J
- Kerrison, C
- Kerslake, I
- Koch, O
- Koduri, G
- Koshy, G
- Laha, S
- Laird, S
- Larkin, S
- Leiner, T
- Lillie, P
- Limb, J
- Linnett, V
- Little, J
- Lyttle, M
- MacMahon, M
- MacNaughton, E
- Mankregod, R
- Masson, H
- Matovu, E
- McCullough, K
- McEwen, R
- Meda, M
- Mills, G
- Minton, J
- Mirfenderesky, M
- Mohandas, K
- Mok, Q
- Moon, J
- Moore, E
- Morgan, P
- Morris, C
- Mortimore, K
- Moses, S
- Mpenge, M
- Mulla, R
- Murphy, M
- Nagel, M
- Nagarajan, T
- Nelson, M
- O'Shea, MK
- Otahal, I
- Ostermann, M
- Pais, M
- Panchatsharam, S
- Papakonstantinou, D
- Paraiso, H
- Patel, B
- Pattison, N
- Pepperell, J
- Peters, M
- Phull, M
- Pintus, S
- Pooni, JS
- Post, F
- Price, D
- Prout, R
- Rae, N
- Reschreiter, H
- Reynolds, T
- Richardson, N
- Roberts, M
- Roberts, D
- Rose, A
- Rousseau, G
- Ryan, B
- Saluja, T
- Shah, A
- Shanmuga, P
- Sharma, A
- Shawcross, A
- Sizer, J
- Shankar-Hari, M
- Smith, R
- Snelson, C
- Spittle, N
- Staines, N
- Stambach, T
- Stewart, R
- Subudhi, P
- Szakmany, T
- Tatham, K
- Thomas, J
- Thompson, C
- Thompson, R
- Tridente, A
- Tupper-Carey, D
- Twagira, M
- Ustianowski, A
- Vallotton, N
- Vincent-Smith, L
- Visuvanathan, S
- Vuylsteke, A
- Waddy, S
- Wake, R
- Walden, A
- Welters, I
- Whitehouse, T
- Whittaker, P
- Whittington, A
- Papineni, P
- Wijesinghe, M
- Williams, M
- Wilson, L
- Cole, S
- Winchester, S
- Wiselka, M
- Wolverson, A
- Wooton, DG
- Workman, A
- Yates, B
- Young, P
- Semple, MG
- Ho, A
- Mark, PB
DOIAbstract
Background Acute kidney injury (AKI) is common in coronavirus disease 2019 (COVID-19). This study investigated adults hospitalized with COVID-19 and hypothesized that risk factors for AKI would include comorbidities and non-White race. Methods A prospective multicentre cohort study was performed using patients admitted to 254 UK hospitals with COVID-19 between 17 January 2020 and 5 December 2020. Results Of 85 687 patients, 2198 (2.6%) received acute kidney replacement therapy (KRT). Of 41 294 patients with biochemistry data, 13 000 (31.5%) had biochemical AKI: 8562 stage 1 (65.9%), 2609 stage 2 (20.1%) and 1829 stage 3 (14.1%). The main risk factors for KRT were chronic kidney disease (CKD) [adjusted odds ratio (aOR)...
Add to ORKG