Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome
- Tariq A. Dam, MD
- Harm-Jan de Grooth, MD, PhD
- Thomas Klausch, PhD
- Lucas M. Fleuren, MD
- Daan P. de Bruin, MSc
- Robert Entjes, MD
- Thijs C. D. Rettig, MD, PhD
- Dave A. Dongelmans, MD, PhD
- Age D. Boelens, MD
- Sander Rigter, MD
- Stefaan H. A. Hendriks, MD
- Remko de Jong, MD
- Marlijn J. A Kamps, MD
- Marco Peters, MD
- A. Karakus, MD
- Diederik Gommers, MD, PhD
- Dharmanand Ramnarain, MD
- Evert-Jan Wils, MD, PhD
- Sefanja Achterberg, MD, PhD
- Ralph Nowitzky, MD
- Walter van den Tempel, MD
- Cornelis P. C. de Jager, MD, PhD
- Fleur G. C. A. Nooteboom, MD
- Evelien Oostdijk, MD, PhD
- Peter Koetsier, MD
- Alexander D. Cornet, MD, PhD, FRCP
- Auke C. Reidinga, MD
- Wouter de Ruijter, MD, PhD
- Rob J. Bosman, MD
- Tim Frenzel, MD, PhD
- Louise C. Urlings-Strop, MD, PhD
- Paul de Jong, MD
- Ellen G. M. Smit, MD
- Olaf L. Cremer, MD, PhD
- D. Jannet Mehagnoul-Schipper, MD, PhD
- Harald J. Faber, MD
- Judith Lens, MD
- Gert B. Brunnekreef, MD
- Barbara Festen-Spanjer, MD
- Tom Dormans, MD, PhD
- Annemieke Dijkstra, MD
- Bram Simons, MD
- A. A. Rijkeboer, MD
- Sesmu Arbous, MD, PhD
- Marcel Aries, MD, PhD
- Menno Beukema, MD
- Daniël Pretorius, MD
- Rutger van Raalte, MD
- Martijn van Tellingen, MD, EDIC
- Niels C. Gritters van den Oever, MD
- Robbert C. A. Lalisang, MD
- Michele Tonutti, MRes
- Armand R. J. Girbes, MD, PhD, EDIC
- Mark Hoogendoorn, PhD
- Patrick J. Thoral, MD, EDIC
- Paul W. G. Elbers, MD, PhD, EDIC
- on behalf of the Dutch ICU Data Sharing Against COVID-19 Collaborators
- Remko van den Akker
- Tom A. Rijpstra
- M. C. Reuland
- Klaas Sierk Arnold
- Arend Jan Meinders
- Nicolas Schroten
- Laura van Manen
- Leon Montenij
- Julia Koeter
- J. W. Fijen
- Jasper van Bommel
- Roy van den Berg
- Martha de Bruin
- Roger van Rietschote
- Ellen van Geest
- Koen S. Simons
- Anisa Hana
- Joost Labout
- Michael Kuiper
- Albertus Beishuizen
- Bart van de Gaauw
- Roos Renckens
- B. van den Bogaard
- Peter Pickkers
- Pim van der Heiden
- Dennis Geutjes
- Claudia (C. W.) van Gemeren
- Emma Rademaker
- Frits H. M. van Osch
- Johan Lutisan
- Jacomar J. M. van Koesveld
- Bart P. Grady
- Martijn de Kruif
- Martin E. Haan
- Luca Roggeveen
- Dagmar M. Ouweneel
- Ronald Driessen
- Jan Peppink
- G. J. Zijlstra
- A. J. van Tienhoven
- Evelien van der Heiden
- Jan Jaap Spijkstra
- Hans van der Spoel
- Angelique de Man
- Heder J. de Vries
- Fuda van Diggelen
- Ali el Hassouni
- David Romero Guzman
- Sandjai Bhulai
- Sebastiaan J. J. Vonk
- Mattia Fornasa
- Tomas Machado
- Adam Izdebski
- Taco Houwert
- Hidde Hovenkamp
- Roberto Noorduijn Londono
- Davide Quintarelli
- Martijn G. Scholtemeijer
- Aletta A. de Beer
- Giovanni Cinà
- Willem E. Herter
- Michael de Neree tot Babberich
- Olivier Thijssens
- Lot Wagemakers
- Hilde G. A. van der Pol
- Tom Hendriks
- Julie Berend
- Virginia Ceni Silva
- Robert F. J. Kullberg
- Leo Heunks
- Nicole Juffermans
- Arjen J. C. Slooter
- Martijn Beudel
- Nicolet F. de Keizer
DOIAbstract
OBJECTIVES:. As coronavirus disease 2019 is a novel disease, treatment strategies continue to be debated. This provides the intensive care community with a unique opportunity as the population of coronavirus disease 2019 patients requiring invasive mechanical ventilation is relatively homogeneous compared with other ICU populations. We hypothesize that the novelty of coronavirus disease 2019 and the uncertainty over its similarity with noncoronavirus disease 2019 acute respiratory distress syndrome resulted in substantial practice variation between hospitals during the first and second waves of coronavirus disease 2019 patients. DESIGN:. Multicenter retrospective cohort study. SETTING:. Twenty-five hospitals in the Netherlands from February...
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