BURDEN OF THYROID DYSFUNCTION IN PATIENTS OF TYPE 2 DIABETES MELLITUS

Objective: To determine the frequency of thyroid disorders in patients of type II diabetes mellitus at Pak Emirates Military Hospital Rawalpindi. Study Design: Cross sectional analytical study. Place and Duration of Study: The study was conducted at Pak Emirates Military Hospital Rawalpindi, from Jul 2017 to Jun 2018. Material and Methods: The study focused on patients with type-II diabetes mellitus presenting to outpatient department of Pak Emirates Military Hospital, Rawalpindi. Ages ranged from 30 years to 70 years and patients who had a previous co-existing thyroid disease or taking drugs that affect thyroid function were excluded. Glycosylated hemoglobin levels were done and Thyroid stimulating hormone levels was used to screen patients for thyroid dysfunction. Results: Mean age of the participants was 54.89 ± 1.10 years. A total of 334 patients [186 (55.7%) males and 148 (44.3%) females] were analysed. Among them 233 patients (69.8%) were euthyroid, 52 patients (15.6%) had subclinical hypothyroidism, 34 patients (10.2%) had subclinical hyperthyroidism, 9 patients (2.7%) had hypothyroidism and 6 patients (1.8%) had hyperthyroidism. Conclusion: The frequency of thyroid disease was significantly higher in patients with type II diabetes mellitus as compared to the general population and thus patients with type II diabetes mellitus should be screened