Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets
A central goal of genetics is to define the phenotypic consequences of genetic perturbations. Single...
International audienceBackground: Multiple studies rely on ChIP-seq experiments to assess the effect...
Among single-cell analysis technologies, single-cell RNA-seq (scRNA-seq) has been one of the front r...
BACKGROUND: Reproducibility of hits from independent CRISPR or siRNA screens is poor. This is partly...
Cells are the basic units of life. Studying complex tissues and whole organs requires an understandi...
Single-cell CRISPR screens enable the exploration of mammalian gene function and genetic regulatory ...
BACKGROUND: Single-cell RNA sequencing (scRNA-seq) has enabled the unbiased, high-throughput quantif...
Single-cell transcriptomics is becoming an important component of the molecular biologist's toolkit....
ooled CRISPR knockout screening is a powerful technique for interrogating the biological function of...
Single-cell RNA-sequencing is a pioneering extension of bulk-base RNA-sequencing technology. The gu...
This research contains two topics: (1) PBNPA: a permutation-based non-parametric analysis of CRISPR ...
© 2020 National Academy of Sciences. All rights reserved. Single-cell quantification of RNAs is impo...
Pooled CRISPR screens are emerging as a powerful tool to dissect regulatory networks, by assessing h...
The RNA-sequencing (RNA-seq) is becoming increasingly popular for quantifying gene expression levels...
Many methods have been used to determine differential gene expression from single-cell RNA (scRNA)-s...
A central goal of genetics is to define the phenotypic consequences of genetic perturbations. Single...
International audienceBackground: Multiple studies rely on ChIP-seq experiments to assess the effect...
Among single-cell analysis technologies, single-cell RNA-seq (scRNA-seq) has been one of the front r...
BACKGROUND: Reproducibility of hits from independent CRISPR or siRNA screens is poor. This is partly...
Cells are the basic units of life. Studying complex tissues and whole organs requires an understandi...
Single-cell CRISPR screens enable the exploration of mammalian gene function and genetic regulatory ...
BACKGROUND: Single-cell RNA sequencing (scRNA-seq) has enabled the unbiased, high-throughput quantif...
Single-cell transcriptomics is becoming an important component of the molecular biologist's toolkit....
ooled CRISPR knockout screening is a powerful technique for interrogating the biological function of...
Single-cell RNA-sequencing is a pioneering extension of bulk-base RNA-sequencing technology. The gu...
This research contains two topics: (1) PBNPA: a permutation-based non-parametric analysis of CRISPR ...
© 2020 National Academy of Sciences. All rights reserved. Single-cell quantification of RNAs is impo...
Pooled CRISPR screens are emerging as a powerful tool to dissect regulatory networks, by assessing h...
The RNA-sequencing (RNA-seq) is becoming increasingly popular for quantifying gene expression levels...
Many methods have been used to determine differential gene expression from single-cell RNA (scRNA)-s...
A central goal of genetics is to define the phenotypic consequences of genetic perturbations. Single...
International audienceBackground: Multiple studies rely on ChIP-seq experiments to assess the effect...
Among single-cell analysis technologies, single-cell RNA-seq (scRNA-seq) has been one of the front r...