The membrane associated accessory protein is an adeno-associated viral egress factor
- Zachary C. Elmore
- L. Patrick Havlik
- Daniel K. Oh
- Leif Anderson
- George Daaboul
- Garth W. Devlin
- Heather A. Vincent
- Aravind Asokan
Publication date
October 2021
DOI Publisher
Springer Science and Business Media LLC Journal
Nature CommunicationsAbstract
Adeno-associated viruses can be secreted in a pre-lytic manner as free or extracellular vesicle (EV)-associated particles. Here, Elmore et al. show that the recently identified membrane-associated accessory protein (MAAP) functions as an AAV egress factor via association to EVs
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