SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike
- Jenna J. Guthmiller
- Olivia Stovicek
- Jiaolong Wang
- Siriruk Changrob
- Lei Li
- Peter Halfmann
- Nai-Ying Zheng
- Henry Utset
- Christopher T. Stamper
- Haley L. Dugan
- William D. Miller
- Min Huang
- Ya-Nan Dai
- Christopher A. Nelson
- Paige D. Hall
- Maud Jansen
- Kumaran Shanmugarajah
- Jessica S. Donington
- Florian Krammer
- Daved H. Fremont
- Andrzej Joachimiak
- Yoshihiro Kawaoka
- Vera Tesic
- Maria Lucia Madariaga
- Patrick C. Wilson
Publication date
February 2021
DOI Publisher
American Society for Microbiology Journal
mBioAbstract
With the ongoing pandemic, it is critical to understand how natural immunity against SARS-CoV-2 and COVID-19 develops. We have identified that subjects with more severe COVID-19 disease mount a more robust and neutralizing antibody response against SARS-CoV-2 spike protein
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