The aim of this study was to describe the appearance and distribution of tissue remodeling markers (MMP-2, MMP-9, TIMP-2, TIMP-4), Sonic hedgehog gene protein (Shh), pro- and anti-inflammatory cytokines (IL–1, IL–10), transcription factor (NF-κβ), proliferation marker (Ki–67), angiogenetic factor (VEGF), tissue defensins (HβD–2, HβD–4) of the pediatric cholesteatoma. Sixteen cholesteatoma samples were obtained from children, eleven skin controls from cadavers. Tissues were stained for MMP-2, MMP-9, TIMP-2, TIMP-4, Shh, IL–1, IL–10, NF-κβ, Ki–67, VEGF, HβD–2, HβD–4. Non-parametric statistic, Mann–Whitney, and Spearman’s coefficient was used. A statistically significant difference was seen between Shh and HβD–2 in perimatrix and control conne...
OBJECTIVES: To investigate whether the expression of the macrophage migration inhibitory factor (MIF...
Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intac...
Hypothesis: This study aimed to analyze the localization and distribution of vessels and of these an...
Background and Objectives. The aim of this study was to compare the distribution of proliferation ma...
Funding Information: Funding: Riga Stradin,š University’s funding is gratefully acknowledged. Publis...
Publisher Copyright: © 2022 Mashhad University of Medical Sciences. All rights reserved.Introduction...
Оbjective: The aim of the current study was: to detect the presence of large and newly form s...
Cholesteatoma is an epidermal cyst with still unknown pathomechanism. The aim of the current study w...
<div><p>Cholesteatoma is an epidermal cyst with still unknown pathomechanism. The aim of the current...
BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and ...
Objective. Cholesteatoma is a clinically heterogeneous disease, with some patients showing spontaneo...
BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and ...
Cholesteatoma is a benign, gradually expanding destructive epithelial lesion of the temporal bone, o...
SummaryCholesteatoma is constituted of matrix, perimatrix and cystic content. Some authors affirm th...
Clinical experience has shown that the otomastoid cholesteatoma is more aggressive and has a less fa...
OBJECTIVES: To investigate whether the expression of the macrophage migration inhibitory factor (MIF...
Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intac...
Hypothesis: This study aimed to analyze the localization and distribution of vessels and of these an...
Background and Objectives. The aim of this study was to compare the distribution of proliferation ma...
Funding Information: Funding: Riga Stradin,š University’s funding is gratefully acknowledged. Publis...
Publisher Copyright: © 2022 Mashhad University of Medical Sciences. All rights reserved.Introduction...
Оbjective: The aim of the current study was: to detect the presence of large and newly form s...
Cholesteatoma is an epidermal cyst with still unknown pathomechanism. The aim of the current study w...
<div><p>Cholesteatoma is an epidermal cyst with still unknown pathomechanism. The aim of the current...
BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and ...
Objective. Cholesteatoma is a clinically heterogeneous disease, with some patients showing spontaneo...
BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and ...
Cholesteatoma is a benign, gradually expanding destructive epithelial lesion of the temporal bone, o...
SummaryCholesteatoma is constituted of matrix, perimatrix and cystic content. Some authors affirm th...
Clinical experience has shown that the otomastoid cholesteatoma is more aggressive and has a less fa...
OBJECTIVES: To investigate whether the expression of the macrophage migration inhibitory factor (MIF...
Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intac...
Hypothesis: This study aimed to analyze the localization and distribution of vessels and of these an...