The selection and spread of antibiotic resistance poses risks to public health by reducing the therapeutic potential of antibiotics against human pathogens. Wastewater-based epidemiology (WBE) is potentially the most reliable approach to estimate antibiotics use. Previous WBE studies used parent antibiotics as biomarkers, which may lead to overestimation since parent antibiotics may be directly disposed of. Using metabolites as biomarkers can avoid this drawback. This study developed a simultaneous solid-phase extraction coupled with ultra-high-performance liquid chromatography tandem mass spectrometry method for analyzing 12 antibiotics and human metabolites in wastewater to help assess health risk. Optimum conditions were achieved using a...
An automated on-line SPE-LC-MS/MS method was developed for the quantitation of multiple classes of a...
Macrolides are widely used in medicine and veterinary medicine, and are the leading antibiotics in t...
The present work describes the development of a fast and robust analytical method for the determinat...
<div><p>A reliable multiclass method has been developed and validated for the determination of eight...
The occurrence of antibiotics in the environment from discharges of wastewater treatment plants (WWT...
This study aimed to identify antimicrobial contaminants in the aquatic environment with effect-direc...
Excessive and inappropriate use of antibiotics contributes to the spread of antibiotic resistance in...
Wastewaters are considered one of the main sources of pollution in the aquatic environment as releas...
Antibiotics are biologically active and are globally used in humans and animal medicine for treatmen...
The mass flows and removal of 20 antibiotics of seven classes in two wastewater treatment plants (WW...
This work described the development, optimization and validation of an analytical method for rapid d...
An analytical method for the analysis of four classes of antibiotics (tetracyclines, sulfonamides, f...
The development of analytical methodologies to monitor different antibiotic families in water and th...
A multi-class method for the simultaneous quantification and confirmation of 47 pharmaceuticals in e...
International audienceIt is well known that pharmaceuticals are not completely removed by convention...
An automated on-line SPE-LC-MS/MS method was developed for the quantitation of multiple classes of a...
Macrolides are widely used in medicine and veterinary medicine, and are the leading antibiotics in t...
The present work describes the development of a fast and robust analytical method for the determinat...
<div><p>A reliable multiclass method has been developed and validated for the determination of eight...
The occurrence of antibiotics in the environment from discharges of wastewater treatment plants (WWT...
This study aimed to identify antimicrobial contaminants in the aquatic environment with effect-direc...
Excessive and inappropriate use of antibiotics contributes to the spread of antibiotic resistance in...
Wastewaters are considered one of the main sources of pollution in the aquatic environment as releas...
Antibiotics are biologically active and are globally used in humans and animal medicine for treatmen...
The mass flows and removal of 20 antibiotics of seven classes in two wastewater treatment plants (WW...
This work described the development, optimization and validation of an analytical method for rapid d...
An analytical method for the analysis of four classes of antibiotics (tetracyclines, sulfonamides, f...
The development of analytical methodologies to monitor different antibiotic families in water and th...
A multi-class method for the simultaneous quantification and confirmation of 47 pharmaceuticals in e...
International audienceIt is well known that pharmaceuticals are not completely removed by convention...
An automated on-line SPE-LC-MS/MS method was developed for the quantitation of multiple classes of a...
Macrolides are widely used in medicine and veterinary medicine, and are the leading antibiotics in t...
The present work describes the development of a fast and robust analytical method for the determinat...