Objective To investigate the possibility of combining tuberculosis (TB)-interferon (IFN)-γ release assays (IGRAs) with lymphocyte enumeration for diagnosis of Mycobacterium tuberculosis infection. Methods We performed a retrospective study of 166 TB patients [68 patients with pulmonary tuberculosis TB (PTB) and 98 patients with extra-pulmonary TB (EPTB)] diagnosed in our hospital between January 2016 and May 2018 along with 377 non-TB patients. The diagnostic performance of the TB-IGRA was evaluated using receiver operating characteristic (ROC) curves. Youden’s index was used to determine the optimal cut-off threshold. Results IFN-γ release in patients with PTB and EPTB were dramatically higher compared with non-TB patients (203.58±18.00 pg...
Early diagnosis of extrapulmonary tuberculosis (EP-TB) is essential. However, diagnosis of EP-TB is ...
Currently available Interferon-γ release assay (IGRA) cannot reliably differentiate active TB (ATB) ...
Interferon (IFN)-γ release assays have limited sensitivity and cannot differentiate between active t...
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (MTB), is a serious infectious dise...
Background The clinical utility of interferon-γ release assays (IGRAs) for diagnosis of active tuber...
Objectives: Currently available interferon (IFN)-γ-release assays (IGRA) cannot discriminate active ...
Since first presentation, Interferon γ Release Assays (IGRAs) have had basic and wide application to...
Abstract Background T-cell interferon-gamma release assays (IGRAs) may have a role in the diagnosis ...
Abstract Background To investigate the diagnostic value of the interferon-γ release assay (IGRA) for...
BACKGROUND: The clinical utility of interferon-γ release assays (IGRAs) for diagnosis of active tube...
Rational Tuberculosis infection (TBI) continues to be a striking global public health problem, incid...
Abstract Background In developing countries, tuberculosis (TB) is a major public health problem and ...
AbstractObjective/BackgroundInterferon (IFN)-γ-release assays (IGRAs) are designed for the diagnosis...
Background: The diagnosis of tuberculosis remains difficult. This study aimed to assess performance ...
To evaluate interleukin (IL)-2 and interferon (IFN)-γ secreting T-cells in parallel for the differen...
Early diagnosis of extrapulmonary tuberculosis (EP-TB) is essential. However, diagnosis of EP-TB is ...
Currently available Interferon-γ release assay (IGRA) cannot reliably differentiate active TB (ATB) ...
Interferon (IFN)-γ release assays have limited sensitivity and cannot differentiate between active t...
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (MTB), is a serious infectious dise...
Background The clinical utility of interferon-γ release assays (IGRAs) for diagnosis of active tuber...
Objectives: Currently available interferon (IFN)-γ-release assays (IGRA) cannot discriminate active ...
Since first presentation, Interferon γ Release Assays (IGRAs) have had basic and wide application to...
Abstract Background T-cell interferon-gamma release assays (IGRAs) may have a role in the diagnosis ...
Abstract Background To investigate the diagnostic value of the interferon-γ release assay (IGRA) for...
BACKGROUND: The clinical utility of interferon-γ release assays (IGRAs) for diagnosis of active tube...
Rational Tuberculosis infection (TBI) continues to be a striking global public health problem, incid...
Abstract Background In developing countries, tuberculosis (TB) is a major public health problem and ...
AbstractObjective/BackgroundInterferon (IFN)-γ-release assays (IGRAs) are designed for the diagnosis...
Background: The diagnosis of tuberculosis remains difficult. This study aimed to assess performance ...
To evaluate interleukin (IL)-2 and interferon (IFN)-γ secreting T-cells in parallel for the differen...
Early diagnosis of extrapulmonary tuberculosis (EP-TB) is essential. However, diagnosis of EP-TB is ...
Currently available Interferon-γ release assay (IGRA) cannot reliably differentiate active TB (ATB) ...
Interferon (IFN)-γ release assays have limited sensitivity and cannot differentiate between active t...