Non-invasive high-frequency oscillatory ventilation in preterm infants after extubation: a randomized, controlled trial
- Yan Li
- Qiufen Wei
- Dan Zhao
- Yan Mo
- Liping Yao
- Lingxiao Li
- Wei Tan
- Xinnian Pan
- Jiayan Yao
- Wei Dai
- Danni Zhong
DOIAbstract
Objective To investigate the effectiveness and safety of non-invasive high-frequency oscillatory ventilation (NHFOV) in post-extubation preterm infants. Methods This was a randomized, controlled trial. A total of 149 preterm infants aged between 25 to 34 weeks’ gestational age with a birth weight of <1500 g who required invasive mechanical ventilation on admission were included. After extubation, they were randomized to the NHFOV group (n = 47), nasal intermittent positive pressure ventilation (NIPPV) group (n = 51), or nasal continuous positive airway pressure (NCPAP) group (n = 51). We compared the effectiveness and safety among these three groups. Results A total of 139 preterm infants finally completed the study. The reintubation rate w...
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