Abstract Natural disasters negatively impact regions and exacerbate socioeconomic vulnerabilities. While the direct impacts of natural disasters are well understood, the channels through which these shocks spread to non-affected regions, still represents an open research question. In this paper we propose modelling socioeconomic systems as spatially-explicit, multi-layer behavioral networks, where the interplay of supply-side production, and demand-side consumption decisions, can help us understand how climate shocks cascade. We apply this modelling framework to analyze the spatial-temporal evolution of vulnerability following a negative food-production shock in one part of an agriculture-dependent economy. Simulation results show that vuln...