Add to ORKGThis study established a regulatory role for the Wnt/ß-catenin pathway in liver progenitor cells (LPCs) in cell culture and in vivo models of non-alcoholic fatty liver disease and demonstrated a significant potential for therapeutic targeting of LPCs with the Wnt inhibitor PRI-724 to inhibit chronic liver disease progression
Background Hepatic progenitor cells (HPCs) hold a great potential for therapeutic intervention for c...
Canonical Wnt signalling, governed by its effector β-catenin, is known for a long time as playing an...
AbstractIn injured livers where hepatocyte growth is severely limited, facultative hepatic stem/prog...
Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely...
Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely...
AbstractIn injured livers where hepatocyte growth is severely limited, facultative hepatic stem/prog...
Background and Aim: Hepatocellular carcinoma (HCC) accounts for 85–90% of primary liver cancers and ...
Owing to its strategic location in the body along with performing over 500 daily functions, liver he...
Hepatic progenitor cells (HPCs) appear to play an important role in chronic liver injury. In this st...
The Wnt/beta-catenin pathway is an evolutionarily conserved signaling cascade with key roles in deve...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
The Wnt/beta-catenin pathway is an evolutionarily conserved signaling cascade with key roles in deve...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
Primary liver cancers (PLCs) are steadily increasing in incidence and mortality in the world. They h...
Background Hepatic progenitor cells (HPCs) hold a great potential for therapeutic intervention for c...
Canonical Wnt signalling, governed by its effector β-catenin, is known for a long time as playing an...
AbstractIn injured livers where hepatocyte growth is severely limited, facultative hepatic stem/prog...
Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely...
Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely...
AbstractIn injured livers where hepatocyte growth is severely limited, facultative hepatic stem/prog...
Background and Aim: Hepatocellular carcinoma (HCC) accounts for 85–90% of primary liver cancers and ...
Owing to its strategic location in the body along with performing over 500 daily functions, liver he...
Hepatic progenitor cells (HPCs) appear to play an important role in chronic liver injury. In this st...
The Wnt/beta-catenin pathway is an evolutionarily conserved signaling cascade with key roles in deve...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
The Wnt/beta-catenin pathway is an evolutionarily conserved signaling cascade with key roles in deve...
Hepatology Characterisation of the liver progenitor cell niche in liver diseases: potential involvem...
Primary liver cancers (PLCs) are steadily increasing in incidence and mortality in the world. They h...
Background Hepatic progenitor cells (HPCs) hold a great potential for therapeutic intervention for c...
Canonical Wnt signalling, governed by its effector β-catenin, is known for a long time as playing an...
AbstractIn injured livers where hepatocyte growth is severely limited, facultative hepatic stem/prog...