Mammalian brains are extremely complex: even the rather small mouse brain contains around one hundred million neurons. Mapping the three-dimensional cytoarchitecture from the nanometer- to centimeter-scale within the context of the entire brain is a key step towards understanding brain function. This thesis presents developments in neuroimaging with virtual histology based on hard X-ray microtomography. This emerging technique holds great promise for non-destructive three-dimensional analysis of centimeter-sized post mortem brain tissue with true micrometer resolution
Accurate knowledge of the morphology of the human brain is required for minimally or non-invasive su...
Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands na...
There is a lack of the necessary methodology for three-dimensional (3D) investigation of soft tissue...
The assessment of three-dimensional (3D) brain cytoarchitecture at a cellular resolution remains a g...
Mammalian brains are extremely complex: a mouse brain contains one hundred million neurons. Mapping ...
Deciphering the three-dimensional (3d) cytoarchitecture of neuronal tissue is an important step towa...
The assessment of neuronal number, spatial organization and connectivity is fundamental for a comple...
The biomedically focused brain research is largely performed on laboratory mice considering a high h...
Sem informaçãoCommonly used methods to visualize the biological structure of brain tissues at subcel...
To quantitatively evaluate brain tissue and its corresponding function, knowledge of the 3D cellular...
Cell visualization and counting plays a crucial role in biological and medical research including th...
X-ray imaging in absorption contrast mode is well established for hard tissue visualization. However...
Softcover, 17x24To bring physiology and pathology of the human brain into better micro-anatomical an...
Knowledge of the three-dimensional (3d) neuronal cytoarchitecture is an important factor in order to...
Background Lewy body disease (LBD) is the second most common cause of neurodegenerative dementia af...
Accurate knowledge of the morphology of the human brain is required for minimally or non-invasive su...
Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands na...
There is a lack of the necessary methodology for three-dimensional (3D) investigation of soft tissue...
The assessment of three-dimensional (3D) brain cytoarchitecture at a cellular resolution remains a g...
Mammalian brains are extremely complex: a mouse brain contains one hundred million neurons. Mapping ...
Deciphering the three-dimensional (3d) cytoarchitecture of neuronal tissue is an important step towa...
The assessment of neuronal number, spatial organization and connectivity is fundamental for a comple...
The biomedically focused brain research is largely performed on laboratory mice considering a high h...
Sem informaçãoCommonly used methods to visualize the biological structure of brain tissues at subcel...
To quantitatively evaluate brain tissue and its corresponding function, knowledge of the 3D cellular...
Cell visualization and counting plays a crucial role in biological and medical research including th...
X-ray imaging in absorption contrast mode is well established for hard tissue visualization. However...
Softcover, 17x24To bring physiology and pathology of the human brain into better micro-anatomical an...
Knowledge of the three-dimensional (3d) neuronal cytoarchitecture is an important factor in order to...
Background Lewy body disease (LBD) is the second most common cause of neurodegenerative dementia af...
Accurate knowledge of the morphology of the human brain is required for minimally or non-invasive su...
Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands na...
There is a lack of the necessary methodology for three-dimensional (3D) investigation of soft tissue...