With the larger variety of methods employed, recanalization therapy is increasingly used to treat acute ischemic stroke resulting in about one-third of patients undergoing early neurological deterioration, in which ischemia/reperfusion injuries are the main cause, leading to increases in the infarcted area, the no-reflow phenomenon, or hemorrhagic transformation. Efficient prevention or treatment of these injuries depends on extensive knowledge of the involved mechanisms. These pathways have dual, damaging, and neuroprotective effects, depending on the timing or protein subtype involved. The current article reviews the main mechanisms contributing to the pathophysiology of these injuries, such as mitochondrial dysfunction, cellular...
Significant advances have been made over the past few years concerning the cellular and molecular ev...
INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellul...
© 2016, International Journal of Pharmacy and Technology. All rights reserved.The most effective tre...
Ischemia is defined as a reduction in blood flow to a level that is sufficient to alter normal cellu...
Cerebral ischemia/reperfusion injury has emerged as an intricate mechanism. However, identification ...
Ischemic stroke is caused by a disruption in blood supply to a region of the brain. It induces dysfu...
Ischemic stroke is caused by a disruption in blood supply to a region of the brain. It induces dysfu...
Pharmacological Neuroprotection in Stroke: Rationale, State-of-the-art and Future Directions Ischemi...
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial...
Stroke is the second leading cause of mortality and the major cause of adult physical disability wor...
Acute ischemic stroke is a common cause of morbidity and mortality worldwide. Thrombolysis with reco...
Its increasing incidence has led stroke to be the second leading cause of death worldwide. Despite s...
Department of Biochemistry and Clinical Biochemistry, Nicolae Testemitanu State University of Medici...
Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic stroke continue t...
The most common type of stroke is ischaemic stroke whereby a blood vessel within the brain is occlud...
Significant advances have been made over the past few years concerning the cellular and molecular ev...
INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellul...
© 2016, International Journal of Pharmacy and Technology. All rights reserved.The most effective tre...
Ischemia is defined as a reduction in blood flow to a level that is sufficient to alter normal cellu...
Cerebral ischemia/reperfusion injury has emerged as an intricate mechanism. However, identification ...
Ischemic stroke is caused by a disruption in blood supply to a region of the brain. It induces dysfu...
Ischemic stroke is caused by a disruption in blood supply to a region of the brain. It induces dysfu...
Pharmacological Neuroprotection in Stroke: Rationale, State-of-the-art and Future Directions Ischemi...
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial...
Stroke is the second leading cause of mortality and the major cause of adult physical disability wor...
Acute ischemic stroke is a common cause of morbidity and mortality worldwide. Thrombolysis with reco...
Its increasing incidence has led stroke to be the second leading cause of death worldwide. Despite s...
Department of Biochemistry and Clinical Biochemistry, Nicolae Testemitanu State University of Medici...
Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic stroke continue t...
The most common type of stroke is ischaemic stroke whereby a blood vessel within the brain is occlud...
Significant advances have been made over the past few years concerning the cellular and molecular ev...
INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellul...
© 2016, International Journal of Pharmacy and Technology. All rights reserved.The most effective tre...