Formerly UNIT 9.15, this unit has been moved to the opening spot of our new chapter on Embryonic Stem Cell technology. The unit has also been updated, and now includes information about the Cre‐lox and FlP/FRT recombinase systems.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/171172/1/cpmb2301.pd
We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryoni...
Journal ArticleGene targeting--homologous recombination of DNA sequences residing in the chromosome ...
Book ChapterGene targeting provides the means for creating strains of mice with mutations in virtual...
The analysis of mutant organisms and cell lines is important in determining the function of specific...
Gene targeting by homologous recombination allows the introduction of specific mutations into any cl...
Gene targeting has been used to direct mutations into specific chromosomal loci in murine embryonic ...
This article has been adapted, with permission, from a paper originally published in Médecine/ Scien...
Conditional mutagenesis in mice is a key approach in neurosciences that makes it possible to investi...
To better understand the mechanism of homologous recombination in mammalian cells that facilitates g...
<p>The endogenous murine <i>c-Myc</i> gene was replaced with a humanized <i>c-Myc</i> gene (<i>hc-My...
Journal ArticleMutations were targeted to the Hprt locus in murine embryonic stem cells by using seq...
AbstractSite-specific recombinase systems (Cre-loxP, Flp-FRT, and φC31-att) are transforming both fo...
The major impact of the human genome sequence is the understanding of disease etiology with deduced ...
We have analyzed the gene-targeting frequencies and recombination products generated by a series of ...
Homologous recombination has been used to introduce site-specific mutations into murine embryonic st...
We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryoni...
Journal ArticleGene targeting--homologous recombination of DNA sequences residing in the chromosome ...
Book ChapterGene targeting provides the means for creating strains of mice with mutations in virtual...
The analysis of mutant organisms and cell lines is important in determining the function of specific...
Gene targeting by homologous recombination allows the introduction of specific mutations into any cl...
Gene targeting has been used to direct mutations into specific chromosomal loci in murine embryonic ...
This article has been adapted, with permission, from a paper originally published in Médecine/ Scien...
Conditional mutagenesis in mice is a key approach in neurosciences that makes it possible to investi...
To better understand the mechanism of homologous recombination in mammalian cells that facilitates g...
<p>The endogenous murine <i>c-Myc</i> gene was replaced with a humanized <i>c-Myc</i> gene (<i>hc-My...
Journal ArticleMutations were targeted to the Hprt locus in murine embryonic stem cells by using seq...
AbstractSite-specific recombinase systems (Cre-loxP, Flp-FRT, and φC31-att) are transforming both fo...
The major impact of the human genome sequence is the understanding of disease etiology with deduced ...
We have analyzed the gene-targeting frequencies and recombination products generated by a series of ...
Homologous recombination has been used to introduce site-specific mutations into murine embryonic st...
We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryoni...
Journal ArticleGene targeting--homologous recombination of DNA sequences residing in the chromosome ...
Book ChapterGene targeting provides the means for creating strains of mice with mutations in virtual...
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