Estimation of Fibrinogen level among Sudanese women with recurrent miscarriage

Background: Recurrent Spontaneous abortion (RSA) is defined as consecutive pregnancy loss before 20 weeks gestation and it has been attributed to either genetic, structural infective, endocrine, immune, or unexplained causes Material and methods: This study was case – control study conducted at the Algophran medical laboratory, Khartoum, Sudan during the period July to November, 2021 and aimed to estimate the fibrinogen level among Sudanese women with recurrent miscarriage. 50 patients attending obstetrics and gynecology unit at Ibrahem Malik   teaching hospital and diagnosed with recurrent spontaneous abortion during the aforementioned period were selected as cases group. In addition to that, 50 apparently healthy women with no history of abortion and without any other risk factor related to abortion were selected as control group. From each participant 5ml of venous blood samples were dispensed into sterile containers with tri-sodium citrate anticoagulant container. Fibrinogen level was estimated by using the coagulometer (Automated Bio Bas)  by BioMed-Fibrinogen kite Result: The results showed; when compared the fibrinogen level between cases and control group there was significant decreased of fibrinogen level with (P = 0.000). Also in the case group there was insignificant differences between fibrinogen level and age , number of miscarriages and the gestational age (P >0.05) Conclusion: In the conclusion the result showed significant decreased of the fibrinogen level and insignificant differences between fibrinogen level and age, number of miscarriages and the gestational age among Sudanese women with recurrent miscarriage. Keywords:  Recurrent Miscarriage, Pregnancy, Fibrinogen, Genetic, Abortion  And Endocrin