Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited data are available on its in vivo genotoxicity. The aim of this study was to evaluate the in vivo genotoxicity of pure CYN (7.5–75 μg/kg body weight) after oral exposure of rats through a combined assay of the micronucleus test (MN) in bone marrow, and the standard and modified comet assay in stomach, liver and blood. Also, histopathological changes in stomach and liver were evaluated. Positive results in the MN test were observed in bone marrow in the exposed rats at all the tested concentrations. However, the comet assay...
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial specie...
Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in t...
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Du...
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide occurrence. The mai...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) is a cyanobacterial toxin found in drinking-water sources world wide. It wa...
Cylindrospermopsin (CYN) is a cyanobacterial toxin found in drinking-water sources world wide. It wa...
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic eff...
Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has ...
Cylindrospermopsin (CYN), a potent cyanobacterial hepatotoxin produced by Cylindrospermopsis racibor...
Cylindrospermopsin (CYN) is a cyanobacterial toxin that is gaining importance, owing to its increasi...
The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different th...
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial specie...
Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in t...
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Du...
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide occurrence. The mai...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in cont...
Cylindrospermopsin (CYN) is a cyanobacterial toxin found in drinking-water sources world wide. It wa...
Cylindrospermopsin (CYN) is a cyanobacterial toxin found in drinking-water sources world wide. It wa...
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic eff...
Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has ...
Cylindrospermopsin (CYN), a potent cyanobacterial hepatotoxin produced by Cylindrospermopsis racibor...
Cylindrospermopsin (CYN) is a cyanobacterial toxin that is gaining importance, owing to its increasi...
The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different th...
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial specie...
Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in t...
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Du...