Study on the Formulation and Characterization of Herbal Toothpaste

The present research work focused on the formulation and characterization of herbal toothpaste from neem oil. Firstly, the physico-chemical properties of Neem seeds (Azadirachtaindica A. Juss) were determined. The Neem oil was extracted from Neem seeds by using solvent extraction process with ethanol (material-to-solvent ratio 1:4 w/v) at extraction temperature 60ºC for 150 min. The physico-chemical characteristics and fatty acid profile of extracted neem oil were also determined using Association of Official Analytical Chemists (AOAC) method and Gas Chromatography (GC). Then, the herbal toothpaste was formulated using extracted neem oil with active and inactive ingredients. The effect of foaming agent, humectant, binder and preservative on the quality of formulated herbal toothpastes were investigated. Finally, the properties such as pH, alkalinity, viscosity, density, lead content, arsenic content, foaming power and physical appearance of formulated herbal toothpastes were also evaluated and compared with commercial product