Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal enzyme β-glucocerebrosidase. Despite the existence of a variety of specific treatments for GD, they cannot completely reverse bone complications. Many studies have evidenced the impairment in bone tissue of GD, and molecular mechanisms of bone density alterations in GD are being studied during the last years and different reports emphasized its efforts trying to unravel why and how bone tissue is affected. The cause of skeletal density affection in GD is a matter of debates between research groups. and there are two opposing hypotheses trying to explain reduced bone mineral density in GD: increased bone resorption versus impaired bone formati...
Gaucher disease (GD) is the most prevalent lysosomal storage disease, and bone involvement is the mo...
Gaucher disease (GD) is a lysosomal storage disorder characterized by accumulation of glucosylcerami...
Gaucher disease (GD) is caused by mutations in the gene GBA1, which encodes for the synthesis of the...
Gaucher disease (GD) is an autosomal recessively inherited lysosomal disorder caused by mutations in...
Gaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to ...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease is a rare autosomal recessive disorder of glycosphingolipid metabolism resulting fro...
Context: Gaucher disease (GD) is a lysosomal storage disorder characterized by abundant presence of ...
Context: Gaucher disease (GD) is a lysosomal storage disorder characterized by abundant presence of ...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
Gaucher disease (GD) is caused by mutations on the gene encoding for the lysosomal enzyme glucocereb...
Gaucher disease, the most common lysosomal storage disorder, is caused by ß-glucocerebrosidase defic...
Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lys...
Gaucher disease (GD) is the most prevalent lysosomal storage disease, and bone involvement is the mo...
Gaucher disease (GD) is a lysosomal storage disorder characterized by accumulation of glucosylcerami...
Gaucher disease (GD) is caused by mutations in the gene GBA1, which encodes for the synthesis of the...
Gaucher disease (GD) is an autosomal recessively inherited lysosomal disorder caused by mutations in...
Gaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to ...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease is a rare autosomal recessive disorder of glycosphingolipid metabolism resulting fro...
Context: Gaucher disease (GD) is a lysosomal storage disorder characterized by abundant presence of ...
Context: Gaucher disease (GD) is a lysosomal storage disorder characterized by abundant presence of ...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
Gaucher disease (GD) is caused by mutations on the gene encoding for the lysosomal enzyme glucocereb...
Gaucher disease, the most common lysosomal storage disorder, is caused by ß-glucocerebrosidase defic...
Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lys...
Gaucher disease (GD) is the most prevalent lysosomal storage disease, and bone involvement is the mo...
Gaucher disease (GD) is a lysosomal storage disorder characterized by accumulation of glucosylcerami...
Gaucher disease (GD) is caused by mutations in the gene GBA1, which encodes for the synthesis of the...