Impact Of Uv-b Rays On Photoaging

Photoaging is an aging process that occurs due to various factors from outside the body such as sunlight. Skin changes that occur are not comprehensive. This happens because Photo aging is a process that involves the reduction of collagen and elastin fiber due to UV radiation from the sun, which has a negative effect on characteristics such as wrinkles, pigmentation spots, decreased skin elasticity and rough texture. The aim of the study was to determine the various variants of ultraviolet B dose to damage to collagen in rat skin. 30 rats were divided into 5 groups of 6 rats each. The control group of 4-month-old mice was left to 7 months (D-0), the other groups treated were divided into 4 groups. The four treatment groups were: administration of UV B 90 mJ / cm2 (Group D1) administration of UV B light 110 mJ / cm2 (Group D2), administration of UV-B light 130 mJ / cm2 (group D3) and administration of UV-B light 150 mJ / cm2 (group D4). Treatment was given to each treatment group for 3 months. The experimental design using a completely randomized design with 5 treatments and 6 replications. Data was analyzed by analysis of variance and followed by LSD Test. Collagen type-1 and MMP-1 expression were measured by immunohistochemical techniques and compared with controls. The results showed that significantly different&nbsp